Several large reviews including thousands of patients have demonstrated that routine pathological examination of operative specimens from uncomplicated primary hip and knee arthroplasty surgeries does not alter patient management or outcome.
Sources:
Campbell ML, et al. Collection of surgical specimens in total joint arthroplasty. Is routine pathology cost effective? J Arthroplasty. J Arthroplasty. 1997 Jan;12(1):60-3. PMID: 9021503.
Kocher MS, et al. Cost and effectiveness of routine pathological examination of operative specimens obtained during primary total hip and knee replacement in patients with osteoarthritis. J Bone Joint Surg Am. 2000 Nov;82-A(11):1531-5. PMID: 11097439.
Lin MM, et al. Histologic examinations of arthroplasty specimens are not cost-effective: a retrospective cohort study. Clin Orthop Relat Res. 2012 May;470(5):1452-60. PMID: 22057818.
Meding JB, et al. Determining the necessity for routine pathologic examinations in uncomplicated total hip and total knee arthroplasties. J Arthroplasty. 2000 Jan;15(1):69-71. PMID: 10654465.