Albumin infusions are part of the acute resuscitation strategy of many burn centres globally, and may be associated with the administration of smaller volumes of crystalloid. Patients with severe burn injuries frequently develop chronic hypoalbuminaemia following resuscitation, due to hypermetabolism, fluid and protein loss from wounds, and impaired albumin synthesis. Attempting to restore serum albumin levels with the continuous infusion of human albumin solutions does not appear to improve outcomes in burn patients, and is costly.
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